Instituut voor Functionele Geneeskunde B.V.


 !  Relevante testpanels bij de volgende lichamelijke condities:

Attention deficit disorder (ADD), attention deficit hyperactive disorder (ADHD)
AIDS
Alzheime's Disease and Memory Functionr
Autism
Cardiovascular Disease
Cystic Fibrosis
Depression and Mood Disorders
Chronic Fatigue Syndrome (CFS)
Fibromyalgia
Headaches and Migraines
Hyperactivity and Attention Deficit Disorder
Inflammatory Bowel Disease (IBD)
Indigestion: gas, bloating, abdominal pain, etc
Lactose Intolerance
Male Infertility
Memory Loss and Senile Dementia
Multiple Sclerosis
Osteoarthritis
Osteoporosis
Premenstrual Syndrome (PMS)
Rheumatoid Arthritis
Sexual Dysfunction and Low Libido
Skin Disorder
Insomnia and Sleep Disorders
Type 2 Diabetes Mellitus
Obesity and Weight Gain

 

Hyperactivity and Attention Deficit Disorder and ADD

Attention deficit disorder (ADD) and attention deficit hyperactive disorder (ADHD) can severely disrupt a child's education and socialization process, incurring life-long effects if not properly diagnosed and treated. Increasingly, there is a tendency to prescribe stimulant medications, such as Ritalin (methylphenidate), to treat these types of disorders. While prescription drugs may sometimes be necessary for treatment of extreme cases, recently there have been reports of an epidemic of hasty misdiagnoses and overprescription. In fact, the rate of methylphenidate prescriptions for children in the U.S. has jumped three to six times in the last decade alone. In some locales, as many as 8-10% of elementary public school children take prescription drugs for ADHD symptoms.

Although drugs can sometimes provide a quick, temporary solution to hyperactivity and attention deficit-related problems, it's important to remember that pharmaceuticals simply treat symptoms of attention deficit disorders--not causes. When medication is stopped, symptoms may promptly return, setting the stage for possible lifelong dependence on prescription drugs. The following GSDL tests can be used to detect possible causes and contributing factors linked to hyperactive behavior in children, and can provide the basis for natural, drug-free alternative methods of treatment.

Hyperactivity and Allergies: Identifying and treating food allergies has proven to be an extremely powerful tool in helping hyperactive children.
Hyperactivity and Element Imbalances: Toxic exposure and nutrient imbalances can have a profound effect on the developing nervous systems of children.
Hyperactivity and Fatty Acids: Studies show fatty acid deficiencies rampant among children with attention deficit hyperactivity disorder.
Hyperactivity and Amino Acids: Amino acids are the body's building blocks for important chemical relaxants in the brain.

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AIDS

AIDS is caused by the HIV (Human Immunodeficiency Virus) virus, a virus found primarily in blood, semen, vaginal secretions, and breast milk. The HIV virus weakens the immune system by infecting and often killing T-helper cells, making the body more vulnerable to a host of other infections. Fever, weight loss, swollen lymph glands, and the development of various cancers and infections are all symptomatic of the disease.
Significant strides against AIDS treatment have been made in recent years, so that increasingly AIDS is being viewed as a chronic disease, rather than a terminal one. Since more patients are living for longer periods with this condition, a holistic, functional approach towards treating the disease is more imperative than ever.

AIDS and Oxidative Stress: Protecting the body against free radical damage can help it better fend off viruses and may slow the progression of AIDS.
AIDS and Male Hormones Males with low circulating levels of testosterone may be more prone to muscle wasting and other symptoms of a more aggressive infection.
AIDS and Digestive Function: AIDS patients often suffer from serious health complications related to impaired digestive function.
AIDS and Adrenal Hormones: Some researchers believe that imbalances of the adrenal hormones cortisol and DHEA suppress immune response and make the body more vulnerable to the viral infections associated with AIDS.
AIDS and Intestinal Permeability: Many individuals with AIDS present with "leaky gut"—damage to the GI barrier that can further compromise health by increasing the penetration of toxins and allergens.
AIDS and Vitamins: Even those who supplement may unknowingly have serious deficiencies of vitamins that can drastically affect the course of AIDS.
AIDS and Fatty Acids: Nutritional imbalances of fatty acids are critical, because they play such a key role in regulating the body's immune response.

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Alzheimer's Disease and Memory Function

Alzheimer's disease is currently the fourth leading cause of death in the U.S. As the baby boom generation ages, the incidence of Alzheimer's disease is expected to skyrocket. Although the symptoms of Alzheimer's usually appear after age 65, it can start developing much earlier–in a person's 40's or 50's. This underscores the need for early use of GSDL functional assessments to optimize the body's natural defenses against the brain neural loss associated with the disease.

Alzheimer's Disease and Adrenal Hormones: Chronic oversecretion of the adrenal stress hormone cortisol is linked to accelerated brain atrophy, while another important adrenal hormone, DHEA, seems to protect the brain from degenerative damage.
Alzheimer's Disease and Oxidative Stress: Increased production of free radicals can damage important brain neurons at the crux of memory function.
Alzheimer's Disease and Fatty Acids: Detecting and treating fatty acid deficiencies seems to improve memory function in many patients with Alzheimers's disease.
Alzheimer's Disease and Menopause: Besides improving bone density and cardiovascular function, the female sex hormone estrogen may protect postmenopausal women from memory loss.
Alzheimer's Disease and Melatonin: One researcher suggests that melatonin imbalances are the main triggers behind memory loss associated with Alzheimer's disease.
Alzheimer's Disease and IGF-1: As levels of growth hormone diminish with age, cognitive ability often steadily declines and symptoms of dementia slowly begin to appear.
Alzheimer's Disease and Element Imbalances: Overexposure to toxins such as mercury, cadmium, and aluminum is linked to severely impaired cognitive function and loss of memory.
Alzheimer's Disease and Amino Acids: Amino acid imbalances can disrupt the production of crucial neurotransmitters in the brain.

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Autism

Autism is a developmental disorder usually diagnosed in early childhood that can manifest in a diverse set of symptoms that range from social and language communication problems, including chronic isolation and lack of verbal response, to mood and behavior disorders that result in aggression, irritability and self-injury.

Autism is more prevalent than previously thought. A recent editorial in the Journal of Pediatrics reported that the condition "appears to be undergoing an almost epidemic increase." Formerly conceived as a "rare condition" that affected only 4 out of every 10,000 children, in recent times the rate has been estimated at nearly 100-fold greater, approaching 1 in100 children or even higher.

Although the precise cause of autism not known, many theories now link the condition to early neurocognitive damage in the brain. Immune dysfunction, toxic exposure, gastrointestinal abnormalities, dietary habits and other factors could interact with various environmental and genetic influences to play a role in autism pathogenesis. Yet because there are many types of autism, ranging widely in their characteristic patterns, each specific case may have a unique set of biochemical factors contributing to the onset and severity of symptoms.

G reat Smokies has created the Autism Resource Center (ARC) web site for both parents and practitioners as an extensive library of information on autism and autistic-spectrum disorders.
The following functional assessments can provide important clues for developing effective customized treatment strategies for each individual.

Autism and Element Imbalances: Exposure to heavy metal toxins, especially when combined with nutrient mineral deficiencies, pose a threat to the healthy neurological development of children.
Autism and Amino Acids: These basic building blocks of proteins form neurotransmitters in the brain that regulate mood and behavior.
Autism and Digestive Function: Autistic children often exhibit chronic digestive problems that are linked to changes in mood and behavior.
Autism and Intestinal Permeability: Many autistic children have "leaky gut," a condition which may increase their body's toxic burden and make them more prone to antibody responses to various environmental antigens.
Autism and Essential Fatty Acids: Significant imbalances of fatty acids in red blood cell membranes have been reported in patients with autism and other similar neuropsychiatric disorders.
Autism and Detoxification: An inability to properly detoxify harmful environmental substances could play an important role in autism.
Autism and Food Sensitivities: Many caregivers of autistic children report a worsening in symptoms after the children eat certain foods.
Autism and Melatonin: Autistic individuals with chronic sleep problems may have a circadian hormone imbalance.

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Cardiovascular Disease

The number one killer in America today, cardiovascular disease claims as many lives as the next 8 leading causes of death combined, including cancer, accidents, and AIDS. Perhaps the greatest tragedy is that this deadly disease is very often preventable. With advances in molecular medicine, researchers have discovered important early indicators that can significantly change the direction of preventative and therapeutic treatment, decreasing the incidence and halting the progression of the disease. The following GSDL assessments are powerful tools for this approach:

Cardiovascular Disease Markers: The most advanced and comprehensive analysis of the biochemical markers associated with heart disease and stroke.
Cardiovascular Disease and Metabolic Dysglycemia: Metabolic dysglycemia sets the stage for numerous degenerative diseases, including diabetes and heart disease.
Cardiovascular Disease and Glucose and Insulin Tolerance: Insulin and glucose imbalances often play a key role in the development of heart disease.
Cardiovascular Disease and Adrenal Hormones: Researchers have recently discovered that DHEA may exert a powerful effect in protecting against cardiovascular disorders.
Cardiovascular Disease and Sex Hormones: Maintaining optimal levels of sex hormones such as estrogen and testosterone has been shown to provide significant cardiovascular benefits.
Cardiovascular Disease and Fatty Acids: Certain dietary fatty acids seem to guard against the hardening of fatty deposits in the arteries.
Cardiovascular Disease and Oxidative Stress: A healthy antioxidant defense helps the body defend against CVD progression mediated by oxidative stress.
Cardiovascular Disease and Element Imbalances: Hypertension and other cardiovascular problems have been linked to toxic and nutrient imbalances.
Cardiovascular Disease and Amino Acids: Amino acids can impact a diverse range of cardiovascular functions.
Cardiovascular Disease and Melatonin: A decrease in melatonin causes increased night-time sympathetic activity, which in turn is linked to coronary disease.

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Cystic Fibrosis

Cystic fibrosis (CF) stems from the faulty transport of sodium and chloride (salt) within epithelial cells to their outer surfaces. This causes the body to produce a thick mucus that can obstruct passageways to the lungs, pancreas, and intestines, leading to severe infections and impaired digestion.

According to the Cystic Fibrosis Foundation, CF is the most common fatal genetic disease in the United States today, affecting approximately 30,000 children and young adults. Each year about 1,000 new cases are diagnosed. The condition can be detected using a specific sweat test that measures salt content. The following GSDL tests can be used to evaluate and treat symptoms and conditions commonly associated with this disease.

Cystic Fibrosis and Digestive Function: Uncover important information about the gut imbalances and pancreatic dysfunctions that commonly occur in conjunction with CF.
Cystic Fibrosis and Intestinal Permeability: The status of the intestine's mucosal lining is a key factor affecting the digestive health of patients with CF.
Cystic Fibrosis and Allergies: Food and environmental allergies are rampant among children with CF.
Cystic Fibrosis and Oxidative Stress: Oxidative damage may lie at the root of various cellular dysfunctions in CF and alter the prognosis for the disease.
Cystic Fibrosis and Fatty Acids: EMFA deficiency may be an important factor in predisposing infants with CF to initially develop respiratory disease.
Cystic Fibrosis and Toxins/Nutrients: Abnormal levels of mineral nutrients have been specifically correlated with growth retardation and severity of pulmonary disease in CF.
Cystic Fibrosis and Vitamins: Shortages of vitamins are linked to increased incidence of neurological complications in CF.
Cystic Fibrosis and Amino Acids: This in-depth analyis can reveal imbalances at the root of fat malabsorption, impaired protein digestion, and other nutritional problems associated with CF.

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Depression and Mood Disorders

Feelings of hopelessness, chronic apathy, and low energy levels are some of the crippling symptoms of depression. Depression can appear as a consequence of a life change such as divorce, death of a family member, or loss of work—or it may insidiously unfold without a clear cause. For this disorder, the well-known adage, "sound body-sound mind" reveals a simple basic truth. That's because depression is commonly intertwined with a vast number of diverse conditions and illnesses--and uncovering potential imbalances can be a powerful tool for an effective natural and holistic approach to emotional healing.

Depression and Amino Acids: The building blocks of protein, amino acids are crucial source material for the production of important brain neurotransmitters. Imbalances can result in several major dysfunctions of the central nervous system linked to depression.
Depression and Thyroid Function: A substantial portion of patients with depression suffer from thyroid hormone imbalances that may make them more treatment-resistant.
Depression and Allergy: Depression seems to predispose individuals to increased immune hypersensitivity to a wide range of food and environmental allergens.
Depression and Melatonin: Imbalances of the pineal hormone melatonin are linked to Seasonal Affective Disorder and other mood and behavior problems. Disrupted secretion patterns of melatonin can also seriously interfere with sleep, worsening existing symptoms of depression.
Depression and Adrenal Hormones: Overly high levels of the adrenal hormone cortisol often underlie the biochemical pattern characteristic of depression, particularly when stress and obesity are also part of the clinical picture.
Depression and Digestive Function: A faulty digestive process can result in the malabsorption of key nutrients necessary for maintaining healthy mood patterns and overall feeling of well-being. Overgrowth of certain intestinal yeasts such as Candida albicans can also trigger mood swings.
Depression and Toxins and Nutrients: Overexposure to heavy metal toxins like lead and mercury have been clinically shown to induce a psychiatric symptoms such as anxiety and depression. Mineral nutrient imbalances can also cause resistance to treatment.
Depression and Glucose and Insulin Tolerance: Fluctuating blood sugar levels, particularly in diabetic patients, can result in increased depression, tension, and fatigue.
Depression and Vitamins: The B-vitamins play an important role in the proper metabolism of important brain neurotransmitters linked to mood and behavior.
Depression and Fatty Acids: Fatty acid deficiencies could significantly contribute to symptoms of depression, particularly in those at high risk of omega-3 deficiencies, such as alcoholics and post partum women.
Depression and Female Hormones: Female hormone imbalances may help explain why women are much more prone to certain types of depression than men.

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Chronic Fatigue Syndrome (CFS):

Chronic Fatigue Syndrome (CFS) is characterized by persistent or relapsing debilitating fatigue for at least 6 months in the absence of any other definable diagnosis. Symptoms of CFS may include depression, hypotension, weight loss, and inability to endure stress.

Over time, CFS can make life miserable, wearing down the body, depressing the spirit, and making a person much more vulnerable to a wide range of related illnesses. Living with CFS can be even more difficult when the individual--and those others around him or her--do not fully understand the factors behind this debilitating condition.

CFS is often part of a complex, multifactorial health condition. There are myriad possible internal and external mechanisms whereby the body's metabolic system can get thrown "out of whack" and induce feelings of exhaustion--and many of these mechanisms are interrelated.
The following are possible underlying causes and contributing factors of both fatigue and Chronic Fatigue Syndrome (CFS). It is important to distinguish between the two conditions, because each one can be triggered by different mechanisms in the body, and thus may have very different diagnostic indicators.

Fatigue and Thyroid Function: Fatigue is a hallmark symptom of thyroid hormone imbalances.
Fatigue and Adrenal Hormones: Chronically high or low levels of powerful adrenal hormones can wear the body down and produce feelings of exhaustion.
Fatigue and Cellular Energy: About 90% of the body's energy is generated by a cellular energy cycle that depends on a healthy balance of organic acids.
Fatigue and Detoxification: Fatigue can develop from toxic stress when the liver is no longer able to detoxify the body's harmful waste by-products and heavy metals begin accumulating from external exposure.
Fatigue and Oxidative Stress: Oxidative stress caused by unstable free radical molecules can damage the energy-producing mechanisms inside the body's cells.
Fatigue and Gastrointestinal Parasites: The incidence of infection from gastrointestinal parasites is increasing in the U.S., and once these microscopic creatures establish themselves inside the GI tract, they can dramatically sap the body's energy.
Fatigue and Digestive Function: Fatigue is often triggered by malabsorption of important nutrients, along with the overgrowth of intestinal yeasts such as Candida albicans.
Fatigue and Glucose and Insulin: Insulin and glucose are two key hormones highly involved in the body's regulatory action of fuel metabolism.
Fatigue and Allergies: Fatigue and allergic sensitivity often go hand-in hand, with a multitude of possible allergenic substances hidden in the food we eat.
Fatigue and Toxins and Nutrients: Exposure to toxins from the environment, especially in combination with key nutrient shortages, can be an insidious source of chronic fatigue.
Fatigue and Fatty Acids: Identifying and treating fatty acid deficiencies has been shown to increase energy levels in many patients with chronic fatigue.
Fatigue and Amino Acids: As the primary source of important proteins, amino acids play a key role in the body's production of energy.

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Fibromyalgia

Fibromyalgia, or Fibromyalgia Syndrome (FMS) is a complex condition triggering chronic, widespread pain and fatigue. As many as 10 million Americans are estimated to have FMS.1
The term "fibromyalgia" comes from the root "fibro-" meaning "fiber" and "-myalgia" meaning "muscle pain". The pain in FMS, however, is actually concentrated in soft tissues (myofascia) at specifically defined "tender points" located around various joints, organs, and other parts of the body.

A specific set of diagnostic criteria for FMS has been set forth by the American Rheumatology Society. Even within these defined parameters, however, fibromyalgia may still manifest with a unique constellation of symptoms in each individual. Associated symptoms can include sleep disturbances, digestive problems, anxiety and depression, headache, and environmental sensitivities (to toxins, allergens, noise, as well as temperature).

Accumulating evidence suggests that FMS is a systemic biochemical condition influenced by multifactorial imbalances throughout the body. Proper testing can identify many of these imbalances, and help determine which interventions are likely to be most effective for each patient.

Fibromyalgia and Cellular Energy: Cells vitally depend on organic acid nutrients to produce energy for muscle and other tissues throughout the body—imbalances can lead to energy depletion and chronic pain
Fibromyalgia and Adrenal Stress: Fibromyalgia has been closely linked with stress-induced imbalances that disrupt the healthy regulation of the body's hormonal and nervous systems
Fibromyalgia and IGF-1: IGF-1 deficiency is a consistent finding in many patients with fibromyalgia, and may be linked to symptoms of fatigue, muscle weakness, and depression
Fibromyalgia and Amino Acids: Imbalances of certain amino acids can trigger primary neurological mechanisms affecting mood and pain sensation, and thus may serve as an important focus for alleviating major symptoms
Fibromyalgia and Element Imbalances: Individuals with fibromyalgia often have physiological systems that are more sensitive to nutrient shortages and toxic exposure
Fibromyalgia and Thyroid Hormones: Some patients with fibromyalgia- including many resistant to conventional treatments for the condition-show clinical signs of thyroid dysfunction
Fibromyalgia and Detoxification: Patients with fibromyalgia may be more sensitive to toxins because their systems are less able to break these substances down and eliminate them from the body
Fibromyalgia and Allergy: A hidden sensitivity to foods or inhalants could set off an inflammatory immune cascade that leads to many classic symptoms of fibromyalgia
Fibromyalgia and Bone Resorption: An abnormally low rate of bone breakdown (resorption) in patients with fibromyalgia may lead to collagen build-up near pain-sensitive nerves
Fibromyalgia and Gastrointestinal Function: The high prevalence of irritable bowel symptoms in patients with fibromyalgia may require specific testing to detect and alleviate common causes of digestive dysfunction
Fibromyalgia and Melatonin: Sleep disturbances and pain sensations in fibromyalgia can be exacerbated if the body's internal biological "clock" is disrupted

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Headaches and Migraines

Researchers have long puzzled over the biochemical mechanisms responsible for recurring headaches and migraines. Recent evidence points to a strong neurochemical influence, with a variety of other possible factors playing an important role in provoking headache pain. The following GSDL tests can uncover functional imbalances linked to recurring headaches and migraines:

Headaches and Allergies: Headache symptoms are often alleviated by pinpointing and eliminating offending foods in the diet provoking allergic reactions.
Headaches and Amino Acids: A variety of amino acid imbalances can trigger chronic headache pain.
Headaches and Female Hormones: For many women, headaches are often associated with menstruation or the onset of menopause.
Headaches and Fatty Acids: Fatty acid imbalances can set the stage for headache pain caused by inflammation.
Headaches and Element Imbalances: A recurrring headache may serve as an important signal of toxic exposure and chronic nutrient imbalances.
Headaches and Vitamin Deficiency: Vitamins A, B, and D play a vital role in a variety of physiological mechanisms underlying headache pain.

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Hyperactivity and Attention Deficit Disorder

Attention deficit disorder (ADD) and attention deficit hyperactive disorder (ADHD) can severely disrupt a child's education and socialization process, incurring life-long effects if not properly diagnosed and treated. Increasingly, there is a tendency to prescribe stimulant medications, such as Ritalin (methylphenidate), to treat these types of disorders. While prescription drugs may sometimes be necessary for treatment of extreme cases, recently there have been reports of an epidemic of hasty misdiagnoses and overprescription. In fact, the rate of methylphenidate prescriptions for children in the U.S. has jumped three to six times in the last decade alone. In some locales, as many as 8-10% of elementary public school children take prescription drugs for ADHD symptoms.

Although drugs can sometimes provide a quick, temporary solution to hyperactivity and attention deficit-related problems, it's important to remember that pharmaceuticals simply treat symptoms of attention deficit disorders--not causes. When medication is stopped, symptoms may promptly return, setting the stage for possible lifelong dependence on prescription drugs. The following GSDL tests can be used to detect possible causes and contributing factors linked to hyperactive behavior in children, and can provide the basis for natural, drug-free alternative methods of treatment.

Hyperactivity and Allergies: Identifying and treating food allergies has proven to be an extremely powerful tool in helping hyperactive children.
Hyperactivity and Element Imbalances: Toxic exposure and nutrient imbalances can have a profound effect on the developing nervous systems of children.
Hyperactivity and Fatty Acids: Studies show fatty acid deficiencies rampant among children with attention deficit hyperactivity disorder.
Hyperactivity and Amino Acids: Amino acids are the body's building blocks for important chemical relaxants in the brain.

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Inflammatory Bowel Disease (IBD)

Inflammatory Bowel Disease (IBD) is characterized by chronic intestinal inflammation that results in clinical symptoms such as diarrhea, bleeding, abdominal pain, fever, joint pain, and weight loss. These symptoms can range from mild to severe, and may gradually and subtly develop from an initial minor discomfort, or may present themselves suddenly with acute intensity.

IBD is a prevalent cause of chronic illness in a large segment of the patient population. It can manifest itself in two different forms: Ulcerative Colitis (UC) and Crohn's Disease (CD). Although the two conditions can appear clinically very similar, UC primarily involves inflammation of the colon and rectum, as opposed to the upper GI tract. Crohn's Disease, on the other hand, impacts a greater area of the upper intestinal digestive tract, and is thus more likely to trigger malabsorption, along with chronic vitamin and nutrient deficiencies.

GSDL offers several assessments that specifically target the physiological mechanisms associated with IBD, allowing physicians to design focused and precise treatment strategies to help prevent development and halt progression of the disease.

IBD and GI Dysbiosis: IBD is believed to develop as a "gut" reaction to intestinal dysbiosis--chronic imbalances in the microbial flora that set off a chain of pathogenic events.
IBD and Intestinal Permeability: A damaged intestinal mucosa triggers and perpetuates IBD by allowing a steady stream of antigens and toxins to continually confront the immune system.
IBD and Parasites: Because certain infectious organisms produce symptoms very similar to IBD, testing for other possible causes is strongly recommended.
IBD and Fatty Acids: The chronic inflammatory immune response that produces many IBD symptoms may be significantly reduced by addressing key imbalances of fatty acids.
IBD and Oxidative Stress: Free radicals mediate the damage to the intestinal outer layer that underlies the progression of IBD.
IBD and Element Imbalances: Levels of zinc, iron, copper and other crucial minerals are often deficient in patients suffering from IBD.
IBD and Allergies: Allergic immune reactions to food particles may play an important role in the development of IBD symptoms.
IBD and Amino Acids: Low levels of important amino acids can provoke aggravated inflammatory responses and may a be a result of IBD-associated malabsorption of nutrients.
IBD and Bone Resorption: Patients with IBD have a higher risk of developing osteoporosis.

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Indigestion: gas, bloating, abdominal pain, etc.

Gastrointestinal (GI) symptoms are among the most common and widespread of health complaints among the general populace. One survey found that over a 3 month period, almost 7 of every 10 American households reported someone suffering from some type of gastrointestinal symptom.1 What's more, a recent Swedish study revealed that, next to headache, gastrointestinal problems are the number one medical complaint among school children.

For successful, long-term treatment, it's crucial to pinpoint the gastrointestinal dysfunctions that underly these complaints, and to exclude the possibility of more serious digestive diseases. In up to 50% of such cases, symptoms are the result of a treatable imbalance within the gastrointestinal tract.

Great Smokies offers several accurate non-invasive assessments that offer clinical insight for treating a wide range of gastrointestinal disorders:

Indigestion and Lactose Intolerance: A simple breath test can reveal one of the most common causes of chronic indigestion—the inability to properly digest lactose, or milk sugar.
Indigestion and Bacterial Overgrowth of the Small Intestine: When gut bacteria overgrow into the small intestine, they can trigger chronic symptoms of maldigestion and malabsorption.
Indigestion and CDSA: This classic functional asssessment provides the most in-depth analysis of malabsorption, maldigestion, and bacterial & yeast imbalances in the gastrointestinal tract.
Indigestion and Parasites: Often unsuspected, an untreated parasitic infection can create chronic symptoms that don't respond to conventional treatments to improve digestive function.

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Lactose Intolerance

Lactose intolerance is one of the most common gastrointestinal disorders, estimated to affect more than 50 million Americans.

This condition arises from an enzyme (lactase) deficiency in the gut. Without adequate amounts of lactase, the digestive system is unable to properly break down and absorb lactose, the main sugar in milk and dairy products. When this happens, lactose is fermented by bacteria in the colon, causing symptoms of bloating, diarrhea, flatulence, and abdominal cramps.
Misdiagnosis of lactose intolerance often occurs because its primary symptoms often overlap with those of other conditions. Clinical evidence indicates that as many as 70% of lactose intolerant patients do not relate their symptoms to lactose ingestion.2 For this reason, the condition is most accurately diagnosed with specific laboratory testing that enables focused, effective treatments.

Lactose Intolerance Breath Test: This sensitive and specific noninvasive test measures the amount hydrogen and methane gases released in response to a lactose challenge drink.
NOTE: The following laboratory evaluations are important for diagnosing other chronic digestive problems that may produce symptoms similar to lactose intolerance:
Bacterial Overgrowth in the Small Intestine Breath Test: Malabsorption symptoms produced by bacterial overgrowth in the small intestine can be almost identical to those of lactose intolerance.
Comprehensive Digestive Stool Analysis: This classic functional asssessment provides the most in-depth analysis of malabsorption, maldigestion, bacterial & yeast imbalances in the GI tract.
Comprehnsive Parasitology Profile: Often unsuspected, an untreated parasitic infection can create chronic symptoms that don't respond to conventional GI treatments.

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Male Infertility

Research studies indicate that sperm counts may be declining worldwide over the last half-century, particularly in men from developed regions such as the United States and Europe. Increased stress, lifestyle changes, and environmental contaminants such as heavy metals, pesticides, and hormone-altering chemicals have been cited as possible causes.

As noted in a recent review on the topic, "a multi-faceted therapeutic approach to improving male fertility involves identifying harmful environmental and occupational risk factors, while correcting underlying nutritional imbalances to encourage optimal sperm production and function."2 The following functional assessments provide valuable clinical guidance in utilizing this approach to optimize sperm quality in men.

Male Infertility and Oxidative Stress: Men with higher levels of free radicals in their bodies have a seven-fold reduced likelihood of initiating a pregnancy.
Male Infertility and Element Imbalances: Male fertility may be impaired by exposure to even "moderate" levels of heavy metals.
Male Infertility and Amino Acids: Amino acids imbalances have been linked to abnormal sperm quality.
Male Infertility and Melatonin: Excess levels of melatonin could be nature's way of "shutting down" sperm production.
Male Infertility and IGF-1: Healthy sperm formation and motility may depend on having adequate levels of IGF-I in the body.

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Memory Loss and Senile Dementia

A recurring memory loss can make daily life extremely frustrating and stressful. If the memory loss is progressive, as in Alzheimer's disease, it may be part of a steady deterioration of brain neurons that eventually creates a state of permanent confusion that can last for years, until the person dies.

Early intervention based on the following GSDL assessments, however, can help safeguard the body's natural protective mechanisms against the brain neural loss associated with impaired memory function.

Memory Loss and Adrenal Hormones: Chronic oversecretion of the adrenal stress hormone cortisol is linked to brain atrophy, while another important adrenal hormone, DHEA, seems to protect the brain from degenerative damage.
Memory and Thyroid Function: Thyroid hormone imbalances, including those triggered by aging, can cause memory and cognitive deficits that improve with accurate diagnosis and treatment.
Memory and Oxidative Stress: Increased production of free radicals can damage important brain neurons at the crux of memory function.
Memory and Fatty Acids: Detecting and treating fatty acid deficiencies seems to improve memory function in many patients with Alzheimers's disease.
Memory and Menopause: Besides improving bone density and cardiovascular function, the female sex hormone estrogen may protect postmenopausal women from memory loss.
Memory Loss and Melatonin: One researcher suggests that melatonin imbalances are the main triggers behind memory loss associated with Alzheimer's disease.
Memory Loss and IGF-1: As levels of growth hormone diminish with age, cognitive ability often steadily declines and symptoms of dementia slowly begin to appear.
Memory Loss and Elemental Imbalances: Overexposure to toxins such as mercury, cadmium, and aluminum is linked to severely impaired cognitive function and loss of memory.
Memory Loss and Amino Acids: Amino acid imbalances can disrupt the production of crucial neurotransmitters in the brain.

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Multiple Sclerosis

Multiple sclerosis (MS) is a disorder characterized by progressive deterioration of the myelin, or fatty sheaths, that protect the nerve axons in the central nervous system. This deterioration impairs the transmission of nerve impulses, resulting in weakness, numbness, locomotor difficulty, pain, loss of vision, and other health problems. MS is viewed as an autoimmune disorder that transpires when internal antibodies mistakenly direct their "attack" against the body's own nerve cells; the disease often unfolds in intermittent periods of relapses and remissions.

Scientists remain puzzled over the precise cause of MS. Although the existence of an instigating viral agent has been hypothesized, and genetic susceptibility seems to play a role, a variety of environmental factors are believed to strongly influence both the onset and progression of this disease. These factors are believed to be multifactorial, and include dietary, metabolic, immunological and hormonal triggers.

The following GSDL assessments can help pinpoint potential triggers implicated in the etiology of MS, and specifically monitor the effectiveness of complementary therapy for MS patients.

Multiple Sclerosis and Essential Fatty Acids: Researchers have linked the increasing prevalence of MS in modern times, along with its unique pattern of geographical incidence, to dietary imbalances of essential fatty acids.Multiple Sclerosis and Allergies: Food allergens may trigger the initial cascade of autoimmune events that characterize MS.
Multiple Sclerosis and Melatonin: Disruptions of pineal gland function have been linked not only to the initial development of MS, but with symptoms of depression that often accompany the disease.
Multiple Sclerosis and Oxidative Stress: Destruction of myelin tissue in MS is primarily mediated by reactive oxygen species in the body.
Multiple Sclerosis and Elemental Imbalances: Several critical nutrient and toxic element imbalances are associated with MS symptoms.
Multiple Sclerosis and Amino Acids: Relapses of MS may be closely related to levels of these fundamental protein constituents.

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Osteoarthritis

The most common type of arthritis, osteoarthritis (also known as degenerative joint disease) strikes over 16 million Americans, and is a major cause of disability among older individuals. Typically osteoarthritis presents as pain, stiffness, or swelling in joints such as the hip, hand, and knee or spine, but it may affect other joints as well. Women run a higher risk of developing osteoarthritis than men, and other risk factors include heredity, excess weight, joint injury, and hormonal imbalances.

Although many people associate osteoarthritis with the "natural" wear and tear of joint cartilage, there are actually a variety of physiological factors that play an important role in the prevention, monitoring, and treatment of this condition. Recently, investigators have strongly emphasized the importance of working to undo actual degenerative mechanisms in the body rather than simply treating symptoms with anti-inflammatory drugs or analgesics.

The following GSDL assessments offer important clinical insight into the dysfunctional mechanisms underlying the development and progression of osteoarthritis.

Osteoarthritis and Bone Resorption: Two collagen crosslinks measured in the urine assess the impact of osteoarthritis upon bone tissue.
Osteoarthritis and IGF-1 Assessment: Insulin-like growth factor (IGF-1) is crucial for maintaining the structural integrity of bone cartilage.
Osteoarthritis and Menopause: Many researchers believe that osteoarthritis in women is triggered by hormonal imbalances in the period following menopause.
Osteoarthritis and Oxidative Stress: Free radicals often mediate the destruction of joint tissue characteristic of osteoarthritis.
Osteoarthritis and Fatty Acids: Inflammatory processes in osteoarthritis can be severely exacerbated by fatty acid imbalances.
Osteoarthritis and Cardiovascular Health: Osteoarthritis places individuals at greater risk for heart disease. A new biomarker, C-reactive protein, serves as an early warning marker for both osteoarthritis and heart disease.
Osteoarthritis and Amino Acids: The building blocks of protein, amino acids are crucial for optimal health of the musculoskeletal system.
Osteoarthritis and Gastrointestinal Health: Chronic use of NSAIDS to treat osteoarthritis can severely damage the gastrointestinal mucosa.

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Osteoporosis

Osteoporosis is the progressive thinning of the bones that takes place when new bone formation does not keep up with bone removal, leaving the bone progressively brittle. As bone is lost, the skeleton continues to have a normal composition, but it becomes porous, hyper-mineralized and more fragile, leading to spinal deformities (dowager's hump) and painful fractures of the wrist, hip and spine.

Osteoporosis is the most common bone disorder in America.1 More than 50% of healthy American women aged 30-40 are likely to develop vertebral fractures as they age due to osteoporosis.2 Unfortunately, treatment is only partially successful (at best) once progressive bone weakening has occurred. It is important to identify women and men who are currently losing bone at an accelerated rate so that effective treatment can begin when the therapeutic burden is prevention instead of reversal of bone loss.
The following GSDL assessments provide crucial information to establish effective intervention strategies against osteoporosis:

Osteoporosis and Bone Resorption: If bone loss is detected early enough, interventions can arrest loss and protect against future osteopororis and bone fractures.
Osteoporosis and IGF-1: Measuring levels of growth hormone can help assess the body's natural ability to preserve and maintain bone density as the body ages.
Osteoporosis and Female Hormones: Deficiencies of important female sex hormones have been clinically linked to increased incidence of osteoporosis.
Osteoporsis and Testosterone: Though osteoporosis chiefly strikes women, one out of every eight men will also fall victim to this disease, and testosterone may play a key role.
Osteoporosis and Adrenal Hormones: The hormones DHEA and cortisol, produced in the body's adrenal glands, have a powerful impact on bone density.
Osteoporosis and Melatonin: A potent antioxidant and modulator of the sleep wake cycle, melatonin actually helps regulate the metabolism of calcium.

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Premenstrual Syndrome

Premenstrual Syndrome (PMS) refers to a set of recurring symptoms arising during the luteal phase of the menstrual cycle, 7-14 days before menses. Irritability, headaches, fatigue, bloating, water retention, breast tenderness, joint pain, acne, depression, nausea, tension, food cravings, pelvic cramping, anxiety, and low sex drive are some of the distressing symptoms that regularly plague women who suffer from PMS.

Although as many as four out of every 10 fertile women experience these symptoms either moderately or severely, until recently these women were afforded little help from conventional medicine.1,2 Based on their own experiences, however, many women have intuitively come to understand the importance of proper exercise, healthy diet, and reduction of stress in lessening the severity of their symptoms.

Clinical studies have uncovered a wide range of physiological imbalances that are believed to trigger or contribute to PMS symptoms. These include female sex hormone imbalances, nutritional deficiencies, imbalances in fatty acid metabolism, yeast overgrowth, thyroid dysfunction, glucose/insulin dysregulation, and disruptions of the body's natural circadian rhythms.

Because of its diverse etiologies, and because symptoms are so varied among women, some researchers have attempted to categorize PMS into different types, each with its own specific causal factors. These classifications are not necessarily consistent among experts, however, and perhaps the wisest approach is to realize that a number of functional imbalances--especially in conjunction with each other--may trigger or exacerbate PMS in its different forms, as well as create other health problems. However, detecting these imbalances early can allow women to alleviate some symptoms of PMS.

PMS and Female Sex Hormones: The symptoms of PMS correlate with specific menstrual cycle changes modulated by the female sex hormones estrogen and progesterone.
PMS and Essential Fatty Acids: Fatty acid imbalances have been linked to many symptoms of PMS including fluid retention and depression.
PMS and Adrenal Stress Hormones: Physical or emotional stress may greatly exacerbate PMS.
PMS and Dysglycemia: The recurrence of certain PMS symptoms, such as food cravings, fatigue, and nervousness, may indicate chronic blood sugar problems.
PMS and Candida Syndrome: Some researchers have proposed that PMS develops when Candida albicans overgrowth impairs the immune system.
PMS and Melatonin Imbalances: PMS can disrupt the body's natural circadian rhythm and interfere with a healthy sleep cycle.
PMS and Elemental Imbalances: Recent studies have linked mineral deficiciencies of calcium and magnesium with the development of PMS.
PMS and Amino Acids: Vitamin B deficiency or tryptophan imbalances may trigger PMS irritability and depression.

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Rheumatoid Arthritis

In rheumatoid arthritis, a dysfunctional immune response causes the joints of the body to become inflamed, leading to severe stiffness and acute and/or chronic pain. An excess of synovial fluid around the joints also contributes to swelling and lack of mobility. All joints are affected by the disease, especially the wrist and hand joints. As the disease progresses, chronic inflammation ultimately destroys cartilage, tendon and ligaments in the elbows, shoulders, knees and ankles.

Rheumatoid arthritis often strikes women and men in the prime of their lives. Symptoms can increase in severity over time, or they may remain relatively constant over the years. Although there is no known cure for this disease, scientists are increasingly discovering the importance of various functional mechanisms in the body that can greatly influence the development and progression of the disease.

The following GSDL tests can expose these imbalances and monitor the effectiveness of treatment, helping patients alleviate some of the debilitating conditions associated with rheumatoid arthritis.

Rheumatoid Arthritis and Oxidative Stress: The oxidative damage caused by free radicals is a pivotal mechanism implicated in the progression of rheumatoid arthritis.
Rheumatoid Arthritis and Sex Hormones: Sex hormones strongly influence the integrity of bone and muscle tissue, and shape many of the general clinical effects of RA.
Rheumatoid Arthritis and Fatty Acids: Fatty acid levels can have a dramatic impact on the inflammatory responses associated with rheumatoid arthritis.
Rheumatoid Arthritis and Digestive Function: Restoring balance to the intestinal microflora has been shown to alleviate many of the symptoms of rheumatoid arthritis.
Rheumatoid Arthritis and Amino Acids: RA therapy often focuses on two important amino acids.
Rheumatoid Arthritis and Element Imbalance: Many patients with rheumatoid arthritis lack essential mineral nutrients.
Rheumatoid Arthritis and Parasitic Infection: An unsuspected parasite infection can trigger symptoms of various types of joint diseases, including RA.

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Sexual Dysfunction and Low Libido

Sexual dysfunction is a common disorder affecting both men and women, and can lead to severe emotional problems such as depression, anxiety, and loss of self esteem. Although the likelihood of sexual dysfunction increases with age, many experts stress that it is not simply a "natural" or "inevitable" consequence of aging.

Impotence is estimated to affect as many as 30 million men in the U.S. alone. After menopause, many women experience a decline in libido, sexual pleasure, and the ability to express orgasm. Some men, too, as they age, experience reduced sex drive and steady decline in sexual ability. Others do not--and the difference often lies in hormone function. Several GSDL tests can uncover imbalances that may be triggering diminishing sex drive, impotence, and other problems of sexual function.

Sexual Dysfunction and Male Hormones: Low libido, weakened sexual performance, and a gradual decrease in the size of sexual organ can be caused by falling levels of testosterone in men as they age.
Sexual Dysfunction and Female Hormones: In women, sex drive and sexual pleasure are directly tied to levels of two important hormones.
Sexual Dysfunction and IGF-1: Growth hormone stimulates many of the body's physiological mechanisms associated with youth, including a strong and healthy sexual function.
Sexual Dysfunction and Elemental Imbalances: Nutrients fuel the body, so key mineral shortages, especially when combined with toxic overload, can seriously impair both sex drive and performance.
Sexual Dysfunction and Amino Acids: Amino acids play a vital role in the mechanisms of sexual arousal.

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Skin Disorders

Classification of skin disorders can be confusing because of overlapping terminology. The common lay term "rash" is loosely used to signify any number of skin disorders characterized by itchy, red, irritated skin eruptions, including dermatitis, eczema, psoriasis, and urticaria (hives). Other common skin problems include acne, keratosis (hardening of the skin), canker sores, premature aging, and dryness.

The largest organ in the human body, skin serves as the crucial mediator between the inner body and the external environment and reflects the status of the body's internal health. Although surface irritants can be the source of skin problems, many skin conditions are actually systemic in origin, and thus may be effectively treated by correcting physiological imbalances within the body.

The following GSDL assessments pinpoint dysfunctions that can trigger a wide range of skin disorders.

Skin Disorders and Allergies: One of the most common causes of dermatitis and eczema is sensitivity to food and/or environmental allergens.
Skin Disorders and Fatty Acids: Dry, itchy, scaly skin is a hallmark sign of essential fatty acid deficiency.
Skin Disorders and Gastrointestinal Dysbiosis: Many skin problems have been linked with imbalances in the gastrointestinal mucosa.
Skin Disorders and Elements: Nutritional imbalances are often first signaled by skin problems.
Skin Disorders (Skin Tone) and IGF-1: Thinning, sagging skin is associated with declining levels of IGF-1.
Skin Disorders (Aging) and Estrogen: Maintaining optimal levels of estrogen can improve improve dryness, wrinkling, fading and other symptoms of skin aging in women.

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Insomnia and Sleep Disorders

Chronic sleep problems can seriously disrupt a person's life, taking a heavy toll in both in personal and professional relationships. And although sleep disorders can be debilitating in and of themselves--over time they can spur additional health problems by weakening the immune system and decreasing natural resistance to infection, depression, cell breakdown, and disease.

The National Institute on Aging has estimated that over 80% of the aged population experience some type of sleep problem at one time or another--with insomnia regularly striking one-fourth of this population.

Besides insomnia, sleep disorders can also take specific forms such as late-phase sleep syndrome, restless legs syndrome, and jet lag.

Sleep Disorders and Melatonin: Melatonin is known as the body's "biological clock," for its crucial role in shaping our physiological responses to the 24-hour cycle.
Sleep Disorders and Adrenal Hormones: High levels of cortisol are associated with stress, restlessness, and the inability to sleep deeply throughout the night.
Sleep Disorders and Amino Acids: The right balance of amino acids can improve the quality of sleep and decrease the time it takes to fall asleep at night.

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Type-2 Diabetes Mellitus

The proper regulation of blood sugar (glucose) is critical for optimal health. Every cell in the body depends on an adequate, yet not excessive, supply of glucose for the energy it requires to function properly.

Type-2 diabetes mellitus is a breakdown in blood sugar regulation that can begin to develop slowly and insidiously in adulthood, or earlier, in adolescence or even childhood. Obesity, sedentary lifestyle, poor diet, and genetic predisposition can gradually desensitize the body to the actions of insulin, the hormone that transports glucose from the bloodstream into cells. Eventually this malfunction may trigger a vicious cycle of imbalances that promotes further obesity and metabolic imbalances.

Inability to maintain normal glucose control can lead to many metabolic diseases, including obesity, heart disease, hypertension, diabetes, chronic fatigue, accelerated aging, as well as numerous mental and emotional disorders. Unfortunately, without early and accurate preventive testing, the first "sign" that surfaces may be a permanent complication from type-2 diabetes such as nerve loss, impotence, or even blindness.

The following functional assessments can detect early signs of glucose and insulin dysregulation that may precede type-2 diabetes by many years. These tests are also important for monitoring the effectiveness of treatments aimed at improving metabolic health.

Type-2 Diabetes and Metabolic Dysglycemia: This test pinpoints pre-diabetic patterns of metabolic dysfunction and can identify at-risk individuals years before permanent complications develop.
Type-2 Diabetes and Cardiovascular Assessment: Diabetes and its related metabolic imbalances are linked to a higher risk of cardiovascular disease.
Type-2 Diabetes and Oxidative Stress: The potential for type-2 diabetes to destroy tissue and damage physiological function may be mediated to a large degree by excess free radicals.
Type-2 Diabetes and Male Hormone Assessment: As men age, declining levels of testosterone may "trigger" metabolic imbalances that promote insulin resistance and type-2 diabetes.
Type-2 Diabetes and Elemental Analysis: Levels of many nutrient and toxic elements are associated with patterns of blood sugar regulation and coronary heart disease risk.
Type-2 Diabetes and Female Hormone Assessment: Imbalances of androgens such as testosterone and DHEA are believed to fuel insulin resistance and central obesity in women.

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Obesity and Weight Gain

Obesity affects much more than a person's appearance and sense of self-esteem--it also represents a serious health risk for a wide range of illnesses and diseases. Often obesity is just one part of a much larger clinical picture of interrelated imbalances inside the body. Besides poor diet and overeating, there are a variety of physiological dysfunctions that can lead to increased fat production and other sources of weight gain.

Weight Gain and Thyroid Hormones: Thyroid hormone imbalances can slow the body's metabolic rate, promoting an increased tendency to put on weight.
Weight Gain and Adrenal Hormones: The adrenal hormones cortisol and DHEA play a major role in the body's fat production, and imbalances may even trigger episodes of binge eating.
Weight Gain and Metabolic Dysglycemia: New research suggests that metabolic dysglycemia and hormonal dysregulation may actually precede and initiate obesity.
Weight Gain and Glucose and Insulin Tolerance: Fluctuating blood sugar levels can lead to increased food cravings, while insulin is directly tied to an individual's degree of body fat.
Weight Gain and Allergies: Many people are unaware that weight gain can be the result of a hidden food allergy.
Weight Gain and Cardiovascular Health: Because obesity greatly increases the likelihood of heart disease, it's best to know how the biochemical environment may also be influencing cardiovascular health.

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©2003 IFG